HORDB

ID: hor003995
Uniprot ID: A0A977SQC6??96-104)
Protein name: Pyrokinin-1
Gene name: NA
Organism: Tenebrio molitor (Yellow mealworm beetle)
Family: Pyrokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Tenebrio (genus), Tenebrioninae (subfamily), Tenebrionidae (family), Tenebrionoidea (superfamily), Cucujiformia (infraorder), Polyphaga (suborder), Coleoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0042811 pheromone biosynthetic process
GO CC: GO:0005576 extracellular region

Sequence: HVVNFTPRL
Length: 9(96-104)
Propeptide: MERIILVNLAVLCVAILLSEVVLSVPHYGSHQVSVRRERNDDKKQSYMWFGPRLGRKKRNSNIDPYRNREREQLATLLDVIQDSPWAIVAVNGKRHVVNFTPRLGRESGEEFVSSAAEDRWLQDPEMSGEMLSQRSPPFAPRLGRHLSPFSPRLGRENDKNLF
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003995_AF2.pdb

hor003995_ESM.pdb

Mass:	122514	Formula:	C50H79N15O12
Absent amino acids:	ACDEGIKMQSWY	Common amino acids:	V
pI:	10.55	Basic residues:	2
Polar residues:	2	Hydrophobic residues:	4
Hydrophobicity:	16.67	Boman Index:	-1281
Half-Life:	3.5 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	107.78
Instability Index:	-1618.89	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18201799
Title: Neuropeptides of the Beetle, Tenebrio Molitor Identified Using MALDI-TOF Mass Spectrometry and Deduced Sequences From the Tribolium Castaneum Genome